
Generated Health has announced a groundbreaking collaboration with Dr. Joshua E. Lowentritt, nationally recognized nephrologist and value-based care leader, to launch an AI-powered chronic kidney disease (CKD) protocol for Florence, the company’s AI Nurse. This partnership will improve CKD patient outcomes, prevent avoidable hospital visits, and give patients the tools to better manage their condition every day.
“We are delighted to team up with Dr. Lowentritt, a leading nephrologist and VBC expert, to develop world-class protocols to automate care for CKD patients,” says Ingolv Urnes, CEO of Generated Health.
His sentiments are echoed by Dr Lowentritt, “I’m excited to work with the smart, dedicated team at Generated Health. They care deeply about improving the patient experience and saving clinical time.”
Why Chronic Kidney Disease Needs a New Approach
Chronic kidney disease affects around 14% of U.S. adults (over 35 million people) with up to 90% unaware of their condition. CKD is a top 10 cause of death in the U.S. and costs Medicare over $77 billion annually. With symptoms often only appearing in advanced stages, early detection, patient activation, and consistent management are critical. While early intervention can dramatically slow disease progression, traditional care models rarely have the resources to provide continuous patient engagement between visits.
“Better patient engagement and education is at the heart of the problem,” explains Dr. Lowentritt. “Florence empowers patients to take control – something no single letter or leaflet can accomplish.”
Florence: AI Powered Support for CKD Management
Florence is an AI virtual nurse that delivers clinically validated, human-like text conversations to patients over weeks and months. She turns medical guidance into bite-sized, actionable insights that patients can follow daily, keeping them engaged long after their clinic visit.
With the new CKD protocol, Florence:
- Teaches patients to recognize early CKD symptoms such as swelling, changes in urination, and shortness of breath
- Reinforces medical advice from nephrologists and primary care providers
- Promotes regular blood pressure and blood sugar checks
- Supports lifestyle changes like low-sodium diets and medication adherence
- Helps prevent unnecessary ER visits and hospital admissions
“The real power of our CKD protocol is patient activation; teaching patients to recognize key symptoms so they avoid the ER, supporting the Triple Aim of higher quality, lower cost, and better patient experience,” highlights Dr. Lowentritt.
Clinician Tested, Patient Approved
Dr. Lowentritt personally tested Florence, experiencing the protocol as if he were a patient.
“I’ve tested Florence by putting myself in the shoes of my patients. The technology combines validated protocols and safe AI. For patients it feels empathetic and human-like, while as a clinician I have 100% control behind the scenes. It’s maybe the most compelling healthcare technology I’ve encountered.”
Florence has already delivered measurable results in hypertension, diabetes, congestive heart failure (CHF), and chronic obstructive pulmonary disease (COPD). The CKD protocol builds on this success to meet the urgent need for better, more consistent CKD management.
“Florence is already proven to deliver strong outcomes across several chronic conditions” according to Dr. Jonathan Serjeant, CMO of Generated Health. “CKD was a natural next step.”
The Future of CKD Care
By combining Dr. Lowentritt’s nephrology expertise with Florence’s AI-driven patient engagement, Generated Health is creating a scalable model for chronic kidney disease care: one that empowers patients, reduces avoidable costs, and gives clinicians more capacity to focus on complex cases.
Learn More About How Florence Works
- How Florence helps manage chronic care?
- Real-world results from Florence deployments?
- Why clinicians trust Florence?
Or email us on info@generatedhealth.com
About Dr. Joshua E. Lowentritt
Dr. Joshua E. Lowentritt is a board-certified Nephrologist and Internal Medicine physician with over two decades of experience. Based in New Orleans, he serves as Medical Director for DaVita Kidney Care and advises Monogram Health and Nephrology Care Alliance. A co-founder of Louisiana Physicians ACO, he is a recognized leader in value-based care and formerly held a senior role at Aledade. Dr. Lowentritt is a passionate advocate for chronic kidney disease education and is particularly focused on the potential of emerging technologies, including AI, to improve outcomes and reduce costs.
About Florence
Florence is a safe, clinically proven virtual nurse who engages patients using empathetic, text-based conversations. She supports patients living with chronic conditions, like CHF, COPD, and now CKD, by collecting readings, reinforcing medical advice, and improving adherence. Florence is used across the U.S., U.K., and Australia in both primary and specialty care settings.